CDC42EP1
Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts. Belongs to the BORG/CEP family. Endothelial and bone marrow stromal cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: GAP; GAP, Rac/Rho |
Chromosomal Location of mouse Ortholog: 15|15 E1 |
Cellular Component:
cytoplasm; cytoskeleton; membrane; plasma membrane
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Molecular Function:
protein binding; small GTPase binding
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Biological Process:
positive regulation of actin filament polymerization; positive regulation of pseudopodium assembly; regulation of cell shape; Rho protein signal transduction
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Reference #:
Q91W92
(UniProtKB)
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Alt. Names/Synonyms: 1810058K22Rik; AA980734; binder of Rho GTPase 5; Binder of Rho GTPases 5; Bor; Borg5; CDC42 effector protein (Rho GTPase binding) 1; Cdc42 effector protein 1; Cdc42ep1; CEP; Cep1; MGC103067; MSE5; MSE55
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Gene Symbols: Cdc42ep1
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Molecular weight:
43,096 Da
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Basal Isoelectric point:
6.68
Predict pI for various phosphorylation states
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