CDC42EP1 Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts. Belongs to the BORG/CEP family. Endothelial and bone marrow stromal cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho
Chromosomal Location of Human Ortholog: 15|15 E1
Cellular Component:  cytoplasm; cytoskeleton; membrane; plasma membrane
Molecular Function:  GTP-Rho binding; protein binding
Biological Process:  positive regulation of actin filament polymerization; positive regulation of pseudopodium assembly; regulation of cell shape; Rho protein signal transduction
Reference #:  Q91W92 (UniProtKB)
Alt. Names/Synonyms: 1810058K22Rik; AA980734; binder of Rho GTPase 5; Binder of Rho GTPases 5; Bor; Borg5; CDC42 effector protein (Rho GTPase binding) 1; Cdc42 effector protein 1; Cdc42ep1; CEP; Cep1; MGC103067; MSE5; MSE55
Gene Symbols: Cdc42ep1
Molecular weight: 43,096 Da
Basal Isoelectric point: 6.68  Predict pI for various phosphorylation states
Select Structure to View Below

CDC42EP1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene