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CHMP7
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway. Belongs to the SNF7 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Chromosomal Location of Human Ortholog: 14|14 D2 |
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Cellular Component:
cytoplasm; cytosol; ESCRT III complex; nuclear envelope; nucleus
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Biological Process:
exit from mitosis; late endosome to vacuole transport; midbody abscission; mitotic metaphase plate congression; nuclear envelope reassembly; nucleus organization; protein localization to chromatin; protein transport; vacuolar transport
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Reference #:
Q8R1T1
(UniProtKB)
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Alt. Names/Synonyms: 4930596K11Rik; 6330407G04Rik; AI450338; AW550775; Charged multivesicular body protein 7; CHMP family, member 7; Chmp7; Chromatin-modifying protein 7; MGC29816
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Gene Symbols: Chmp7
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Molecular weight:
50,633 Da
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Basal Isoelectric point:
5.15
Predict pI for various phosphorylation states
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