EIF5B Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. Belongs to the IF-2 family. Note: This description may include information from UniProtKB.
Protein type: Translation; Translation initiation
Chromosomal Location of Human Ortholog: 1|1 B
Cellular Component:  cytoplasm
Molecular Function:  GTP binding; GTPase activity; hydrolase activity; metal ion binding; nucleotide binding; translation initiation factor activity
Biological Process:  regulation of translational initiation
Reference #:  Q05D44 (UniProtKB)
Alt. Names/Synonyms: A030003E17Rik; BC018347; eIF-5B; Eif5b; Eukaryotic translation initiation factor 5B; If2; IF2P; Translation initiation factor IF-2
Gene Symbols: Eif5b
Molecular weight: 137,616 Da
Basal Isoelectric point: 5.47  Predict pI for various phosphorylation states
CST Pathways:  Translation: eIF2  |  Translational Control
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene