IPO3 iso3 Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains. Expressed in skeletal muscle. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Karyopherin; Nuclear export; Nuclear import; Receptor, misc.
Chromosomal Location of Human Ortholog: 6 A3.3|6 12.36 cM
Cellular Component:  cytoplasm; intracellular membrane-bounded organelle; nucleus
Molecular Function:  identical protein binding
Biological Process:  protein import into nucleus
Reference #:  Q6P2B1-3 (UniProtKB)
Alt. Names/Synonyms: 5730544L10Rik; C430013M08Rik; C81142; D6Ertd313; D6Ertd313e; IPO3 iso3; KIAA4133; MGC90049; mKIAA4133; Tnpo3; transportin 3; Transportin-3; transportin-SR; Trn-SR
Gene Symbols: Tnpo3
Molecular weight: 29,915 Da
Basal Isoelectric point: 5.7  Predict pI for various phosphorylation states
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IPO3 iso3

Protein Structure Not Found.


Cross-references to other databases:  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene