DDX16 Required for pre-mRNA splicing as component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily. Note: This description may include information from UniProtKB.
Protein type: EC; Helicase; RNA processing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 17|17 B1
Cellular Component:  nucleoplasm; nucleus; spliceosomal complex; U2-type precatalytic spliceosome
Molecular Function:  ATP-dependent 3'-5' RNA helicase activity; ATPase activity; RNA binding
Biological Process:  mRNA splicing, via spliceosome
Reference #:  G3X8X0 (UniProtKB)
Alt. Names/Synonyms: 2410006N22Rik; DBP2; Ddx16; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; Dhx16; mKIAA0577; MKIAA0577 protein
Gene Symbols: Dhx16
Molecular weight: 119,072 Da
Basal Isoelectric point: 6.21  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein