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DDX16
Required for pre-mRNA splicing as component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.6.4.13; Helicase; RNA processing; RNA-binding; Spliceosome |
| Chromosomal Location of mouse Ortholog: 17|17 B1 |
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Cellular Component:
cytoplasm; intracellular anatomical structure; nucleoplasm; nucleus; spliceosomal complex; U2-type precatalytic spliceosome
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Molecular Function:
helicase activity; molecular adaptor activity; pattern recognition receptor activity; RNA binding; RNA helicase activity; ubiquitin binding
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Biological Process:
antiviral innate immune response; mRNA splicing, via spliceosome
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Reference #:
G3X8X0
(UniProtKB)
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Alt. Names/Synonyms: 2410006N22Rik; DBP; DBP2; Ddx16; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; Dhx16; mKIAA0577; MKIAA0577 protein; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; RNA helicase
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Gene Symbols: Dhx16
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Molecular weight:
119,072 Da
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Basal Isoelectric point:
6.21
Predict pI for various phosphorylation states
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