SAPAP4 May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Membrane protein, peripheral
Chromosomal Location of mouse Ortholog: 2|2 H1
Cellular Component:  cholinergic synapse; dendrite; glutamatergic synapse; membrane; neuromuscular junction; neuronal cell body; plasma membrane; postsynaptic specialization; synapse
Molecular Function:  protein binding; protein domain specific binding
Biological Process:  signaling
Reference #:  B1AZP2 (UniProtKB)
Alt. Names/Synonyms: AI225853; BC024558; DAP-4; DAP4; discs, large homolog-associated protein 4; discs, large homolog-associated protein 4 (Drosophila); Disks large-associated protein 4; DLG associated protein 4; Dlgap4; DLGP4; Kiaa0964; MGC117830; MGC37636; mKIAA0964; OTTMUSP00000017143; OTTMUSP00000017145; PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4; SAPAP-4; Sapap4; WBP1; WBP16; WW domain-binding protein 16
Gene Symbols: Dlgap4
Molecular weight: 108,037 Da
Basal Isoelectric point: 6.65  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene