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ABCF1
Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: RNA-binding; Translation |
| Chromosomal Location of mouse Ortholog: 17 B1|17 18.8 cM |
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Cellular Component:
cytoplasm; cytosol; nuclear envelope; nucleoplasm; nucleus; polysomal ribosome; ribosome
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Molecular Function:
ATP binding; ATP hydrolysis activity; nucleotide binding; ribosome binding; translation activator activity
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Biological Process:
positive regulation of translation; translational initiation
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Reference #:
Q6P542
(UniProtKB)
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Alt. Names/Synonyms: Abc5; Abc50; Abcf1; ATP-binding cassette sub-family F member 1; ATP-binding cassette, sub-family F (GCN20), member 1; AU041969; D17Wsu166; D17Wsu166e; GCN2; GCN20
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Gene Symbols: Abcf1
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Molecular weight:
94,945 Da
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Basal Isoelectric point:
6.15
Predict pI for various phosphorylation states
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