an AGC kinase that plays a critical role in controlling the balance between survival and apoptosis. Stimulated by platelet-derived growth factor, insulin, and insulin-like growth factor 1. Alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: AGC group; AKT family; EC 22.214.171.124; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor)
Molecular Function: ATP binding; protein binding; protein kinase activity; protein serine/threonine kinase activity
Biological Process: brain morphogenesis; homeostasis of number of cells within a tissue; mitochondrial genome maintenance; negative regulation of cellular senescence; positive regulation of artery morphogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of cell migration involved in sprouting angiogenesis; positive regulation of cell size; positive regulation of endothelial cell proliferation; positive regulation of TOR signaling; positive regulation of vascular endothelial cell proliferation; protein phosphorylation; signal transduction