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SKIC2
Helicase; has ATPase activity. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). Belongs to the helicase family. SKI2 subfamily. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.6.1.-; EC 3.6.4.-; Helicase |
| Chromosomal Location of mouse Ortholog: 17|17 B1 |
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Cellular Component:
Ski complex
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Molecular Function:
3'-5' RNA helicase activity; RNA helicase activity
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Biological Process:
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; rescue of stalled ribosome
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Reference #:
Q6NZR5
(UniProtKB)
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Alt. Names/Synonyms: 4930534J06Rik; AW214248; Ddx13; helicase SKI2W; SKI; SKI2 subunit of superkiller complex; Ski2w; Skic2; Skiv2l; Superkiller complex protein 2; superkiller viralicidic activity 2-like; Superkiller viralicidic activity 2-like (S. cerevisiae)
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Gene Symbols: Skic2
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Molecular weight:
137,524 Da
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Basal Isoelectric point:
5.88
Predict pI for various phosphorylation states
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