ATRIP Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. Belongs to the ATRIP family. Ubiquitous. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; DNA repair, damage; DNA-binding
Chromosomal Location of Human Ortholog: 9|9 F2
Cellular Component:  nucleus
Molecular Function:  K63-linked polyubiquitin modification-dependent protein binding; protein binding
Biological Process:  cellular response to DNA damage stimulus; DNA damage checkpoint; DNA repair
Reference #:  Q8BMG1 (UniProtKB)
Alt. Names/Synonyms: 6620401K05Rik; ATM and Rad3 related interacting protein; ATM and Rad3-related-interacting protein; ATR interacting protein; ATR-interacting protein; Atrip; MGC90531
Gene Symbols: Atrip
Molecular weight: 85,548 Da
Basal Isoelectric point: 5.84  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene