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ATRIP
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. Belongs to the ATRIP family. Ubiquitous. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell cycle regulation; DNA repair, damage; DNA-binding |
| Chromosomal Location of human Ortholog: 3p21.31 |
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Cellular Component:
ATR-ATRIP complex; nucleoplasm; nucleus
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Molecular Function:
K63-linked polyubiquitin modification-dependent protein binding; protein binding
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Biological Process:
DNA damage checkpoint signaling; DNA repair; nucleobase-containing compound metabolic process; regulation of double-strand break repair
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Reference #:
Q8WXE1
(UniProtKB)
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Alt. Names/Synonyms: AGS1; ATM and Rad3-related-interacting protein; ATR interacting protein; ATR-interacting protein; ATRIP; DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740
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Gene Symbols: ATRIP
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Molecular weight:
85,838 Da
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Basal Isoelectric point:
5.9
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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