SREC Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component:  endocytic vesicle membrane; integral component of membrane; plasma membrane
Molecular Function:  low-density lipoprotein particle binding; scavenger receptor activity; transmembrane signaling receptor activity
Biological Process:  cell adhesion; cholesterol catabolic process; dendrite development; neuron remodeling; positive regulation of axon regeneration; positive regulation of neuron projection development; receptor-mediated endocytosis
Reference #:  Q14162 (UniProtKB)
Alt. Names/Synonyms: Acetyl LDL receptor; Endothelial cells scavenger receptor; KIAA0149; MGC47738; SCARF1; Scavenger receptor class F member 1; scavenger receptor class F, member 1; scavenger receptor expressed by endothelial cells; SREC
Gene Symbols: SCARF1
Molecular weight: 87,387 Da
Basal Isoelectric point: 5.98  Predict pI for various phosphorylation states
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SREC

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein