EPB41L1 May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of mouse Ortholog: 2 H1|2 77.39 cM
Cellular Component:  cytoplasm; cytoskeleton; cytosol; plasma membrane; postsynaptic density; protein-containing complex; synaptic membrane
Molecular Function:  actin binding; cytoskeletal protein binding; protein binding; signaling receptor binding; structural molecule activity
Biological Process:  actomyosin structure organization; cortical actin cytoskeleton organization
Reference #:  Q9Z2H5 (UniProtKB)
Alt. Names/Synonyms: 4.1; 4.1N; Band 4.1-like protein 1; E41L1; Epb4; Epb4.1; Epb4.1l1; Epb41l1; erythrocyte membrane protein band 4.1 like 1; erythrocyte protein band 4.1 like 1; erythrocyte protein band 4.1-like 1; Kiaa0338; mKIAA0338; NBL1; Neuronal protein 4.1; OTTMUSP00000016920; OTTMUSP00000016923; OTTMUSP00000017082
Gene Symbols: Epb41l1
Molecular weight: 98,315 Da
Basal Isoelectric point: 5.43  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene