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KIF21B
Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Microtubule-binding; Motor |
| Chromosomal Location of Human Ortholog: 1 E4|1 59.61 cM |
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Cellular Component:
cell projection; cytoplasm; cytoplasmic vesicle; cytoskeleton; kinesin complex; microtubule
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Molecular Function:
ATP binding; ATPase activity; microtubule binding; microtubule motor activity; nucleotide binding
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Biological Process:
microtubule-based movement
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Reference #:
Q9QXL1
(UniProtKB)
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Alt. Names/Synonyms: 2610511N21Rik; KI21B; KIAA0449; Kif21b; Kif6; kinesin family member 21B; Kinesin-like protein KIF21B; Kinesin-like protein KIF6; mKIAA0449; N-5 kinesin
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Gene Symbols: Kif21b
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Molecular weight:
186,180 Da
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Basal Isoelectric point:
6.71
Predict pI for various phosphorylation states
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