KIF21B Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 1 E4|1 59.61 cM
Cellular Component:  cell projection; cytoplasm; cytoplasmic vesicle; cytoskeleton; kinesin complex; microtubule
Molecular Function:  ATP binding; ATPase activity; microtubule binding; microtubule motor activity; nucleotide binding
Biological Process:  microtubule-based movement
Reference #:  Q9QXL1 (UniProtKB)
Alt. Names/Synonyms: 2610511N21Rik; KI21B; KIAA0449; Kif21b; Kif6; kinesin family member 21B; Kinesin-like protein KIF21B; Kinesin-like protein KIF6; mKIAA0449; N-5 kinesin
Gene Symbols: Kif21b
Molecular weight: 186,180 Da
Basal Isoelectric point: 6.71  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene