CHRAC1 Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of mouse Ortholog: 15|15 D3
Cellular Component:  CHRAC; nucleus; pericentric heterochromatin
Molecular Function:  DNA binding; DNA-directed DNA polymerase activity; nucleotidyltransferase activity; protein binding; protein heterodimerization activity; transferase activity
Biological Process:  chromatin remodeling; nucleosome assembly; regulation of DNA replication
Reference #:  Q9JKP8 (UniProtKB)
Alt. Names/Synonyms: 2410152E03Rik; 2810406L04Rik; CHRAC-1; Chrac1; CHRC1; chromatin accessibility complex 1; Chromatin accessibility complex protein 1; DNA polymerase epsilon subunit p15; NF-YC-like protein; YC-like protein 1; YCL; YCL1
Gene Symbols: Chrac1
Molecular weight: 14,127 Da
Basal Isoelectric point: 5.1  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene