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CHRAC1
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding |
| Chromosomal Location of Human Ortholog: 15|15 D3 |
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Cellular Component:
CHRAC; nucleus
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Molecular Function:
DNA binding; DNA-directed DNA polymerase activity; nucleotidyltransferase activity; protein binding; protein heterodimerization activity; transferase activity
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Biological Process:
heterochromatin organization involved in chromatin silencing
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Reference #:
Q9JKP8
(UniProtKB)
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Alt. Names/Synonyms: 2410152E03Rik; 2810406L04Rik; CHRAC-1; Chrac1; CHRC1; chromatin accessibility complex 1; Chromatin accessibility complex protein 1; DNA polymerase epsilon subunit p15; NF-YC-like protein; YC-like protein 1; YCL1
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Gene Symbols: Chrac1
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Molecular weight:
14,127 Da
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Basal Isoelectric point:
5.1
Predict pI for various phosphorylation states
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