ITIH2 May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Belongs to the ITIH family. Plasma. Note: This description may include information from UniProtKB.
Protein type: Inhibitor; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 2 A1|2 6.89 cM
Cellular Component:  extracellular region
Molecular Function:  peptidase inhibitor activity; serine-type endopeptidase inhibitor activity
Biological Process:  hyaluronan metabolic process; negative regulation of peptidase activity
Reference #:  Q61703 (UniProtKB)
Alt. Names/Synonyms: AI747202; inter-alpha trypsin inhibitor, heavy chain 2; Inter-alpha-inhibitor heavy chain 2; Inter-alpha-trypsin inhibitor heavy chain H2; Intin2; ITI heavy chain H2; ITI-HC2; Itih; Itih-2; Itih2; OTTMUSP00000012019
Gene Symbols: Itih2
Molecular weight: 105,928 Da
Basal Isoelectric point: 6.82  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene