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ITIH2
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Belongs to the ITIH family. Plasma. Note: This description may include information from UniProtKB.
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| Protein type: Inhibitor; Secreted; Secreted, signal peptide |
| Chromosomal Location of mouse Ortholog: 2 A1|2 6.89 cM |
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Cellular Component:
extracellular region
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Molecular Function:
hyaluronic acid binding; peptidase inhibitor activity; serine-type endopeptidase inhibitor activity
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Biological Process:
hyaluronan metabolic process; negative regulation of peptidase activity
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Reference #:
Q61703
(UniProtKB)
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Alt. Names/Synonyms: AI747202; inter-alpha trypsin inhibitor, heavy chain 2; Inter-alpha-inhibitor heavy chain 2; Inter-alpha-trypsin inhibitor heavy chain H2; Intin2; ITI heavy chain H2; ITI-HC2; Itih; Itih-2; Itih2; OTTMUSP00000012019
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Gene Symbols: Itih2
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Molecular weight:
105,928 Da
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Basal Isoelectric point:
6.82
Predict pI for various phosphorylation states
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