STMN3 Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. Belongs to the stathmin family. Neuron specific. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 2|2 H4
Cellular Component:  cell projection; cytoplasm; Golgi apparatus; neuron projection; perinuclear region of cytoplasm
Molecular Function:  protein binding; protein C-terminus binding; protein domain specific binding; tubulin binding
Biological Process:  blastocyst hatching; cytoplasmic microtubule organization; microtubule depolymerization; negative regulation of Rac protein signal transduction; neuron projection development; regulation of cytoskeleton organization; regulation of GTPase activity; regulation of microtubule polymerization or depolymerization
Reference #:  O70166 (UniProtKB)
Alt. Names/Synonyms: 9330161A03Rik; AI604839; Hippocampus abundant transcript 3; OTTMUSP00000018010; R75323; SCG10-like protein; SCG10-related protein HiAT3; Scgn10 like-protein; Sclip; Stathmin-3; stathmin-like 3; Stmn3
Gene Symbols: Stmn3
Molecular weight: 20,954 Da
Basal Isoelectric point: 6.99  Predict pI for various phosphorylation states
CST Pathways:  Microtubule Dynamics
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene