HDGF Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. Belongs to the HDGF family. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Transcription regulation
Chromosomal Location of Human Ortholog: 3 F1|3 38.78 cM
Cellular Component:  cytoplasm; extracellular space; nucleoplasm; nucleus; transcriptional repressor complex
Molecular Function:  DNA binding; growth factor activity; heparin binding; nucleotide binding; protein binding; transcription corepressor activity
Biological Process:  cellular process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein localization to nucleus; regulation of transcription, DNA-templated; transcription, DNA-dependent
Reference #:  P51859 (UniProtKB)
Alt. Names/Synonyms: AI118077; D3Ertd299e; HDGF; Hepatoma-derived growth factor; Tdrm1
Gene Symbols: Hdgf
Molecular weight: 26,269 Da
Basal Isoelectric point: 4.8  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene