HDGF Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. Belongs to the HDGF family. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Transcription regulation
Chromosomal Location of Human Ortholog: 3 F1|3 38.78 cM
Cellular Component:  cytoplasm; extracellular space; nucleoplasm; nucleus; transcriptional repressor complex
Molecular Function:  DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; growth factor activity; heparin binding; nucleotide binding; protein binding; RNA polymerase II proximal promoter sequence-specific DNA binding; transcription corepressor activity; transcription corepressor binding
Biological Process:  cellular process; cellular response to interleukin-7; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; protein localization to nucleus
Reference #:  P51859 (UniProtKB)
Alt. Names/Synonyms: AI118077; D3Ertd299e; HDGF; Hepatoma-derived growth factor; Tdrm1
Gene Symbols: Hdgf
Molecular weight: 26,269 Da
Basal Isoelectric point: 4.8  Predict pI for various phosphorylation states
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HDGF

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene