| RPS27 Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs. Belongs to the eukaryotic ribosomal protein eS27 family. Expressed in a wide variety of actively proliferating cells and tumor tissues. Note: This description may include information from UniProtKB. |
| Protein type: Ribosomal; Translation |
| Chromosomal Location of human Ortholog: 1q21.3 |
| Cellular Component: cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; nucleus; postsynaptic density; ribosome; small-subunit processome |
| Molecular Function: DNA binding; protein binding; RNA binding; structural constituent of ribosome; zinc ion binding |
| Biological Process: cytoplasmic translation; ribosomal small subunit assembly; ribosomal small subunit biogenesis; rRNA processing; translation |
| Disease: Diamond-blackfan Anemia 17 |
| Reference #: P42677 (UniProtKB) |
| Alt. Names/Synonyms: 40S ribosomal protein S27; DBA17; Metallopan-stimulin 1; metallopanstimulin 1; MPS-1; MPS1; ribosomal protein S27; RPS27; RS27; S27; Small ribosomal subunit protein eS27 |
| Gene Symbols: RPS27 |
| Molecular weight: 9,461 Da |
| Basal Isoelectric point: 9.57 Predict pI for various phosphorylation states |
| Select Structure to View Below |
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RPS27 |
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Cross-references to other databases:
AlphaFold
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STRING
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cBioPortal
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Wikipedia
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Reactome
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neXtProt
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Protein Atlas
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BioGPS
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Pfam
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