LAPTM5 May have a special functional role during embryogenesis and in adult hematopoietic cells. Belongs to the LAPTM4/LAPTM5 transporter family. Preferentially expressed in adult hematopoietic tissues. High levels in lymphoid and myeloid tissues. Highly expressed in peripheral blood leukocytes, thymus, spleen and lung, followed by placenta, liver and kidney. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Vesicle
Chromosomal Location of human Ortholog: 1p35.2
Cellular Component:  integral component of plasma membrane; lysosomal membrane; lysosome
Molecular Function:  protein binding
Biological Process:  cellular response to leukemia inhibitory factor
Reference #:  Q13571 (UniProtKB)
Alt. Names/Synonyms: CD40-ligand-activated specific transcripts; CLAST6; FLJ61683; FLJ97251; human retinoic acid-inducible E3 protein; KIAA0085; LAPM5; LAPTM5; lysosomal associated multispanning membrane protein 5; lysosomal multispanning membrane protein 5; lysosomal protein transmembrane 5; Lysosomal-associated multitransmembrane protein 5; Lysosomal-associated transmembrane protein 5; MGC125860; MGC125861; Retinoic acid-inducible E3 protein
Gene Symbols: LAPTM5
Molecular weight: 29,937 Da
Basal Isoelectric point: 8.95  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene