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NCAM1
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell adhesion; Membrane protein, GPI anchor; Membrane protein, integral; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 9 A5.3|9 26.83 cM |
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Cellular Component:
axon; cell surface; cell-cell junction; cytosol; external side of plasma membrane; glutamatergic synapse; growth cone; membrane; neuronal cell body; plasma membrane; postsynaptic membrane; presynaptic membrane; Schaffer collateral - CA1 synapse
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Molecular Function:
heparin binding; LRR domain binding; phosphatase binding; protein binding
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Biological Process:
axonal fasciculation; calcium-mediated signaling; cell adhesion; cell surface receptor signaling pathway; commissural neuron axon guidance; epithelial to mesenchymal transition; homotypic cell-cell adhesion; learning or memory; modulation of chemical synaptic transmission; multicellular organismal response to stress; negative regulation of programmed cell death; neuron development; neuron projection development; positive regulation of calcium-mediated signaling; positive regulation of cardiac muscle cell proliferation; regulation of exocyst assembly; regulation of semaphorin-plexin signaling pathway; response to cocaine; response to lead ion; response to xenobiotic stimulus; thalamus development
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Reference #:
P13595
(UniProtKB)
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Alt. Names/Synonyms: CD56; E-NC; E-NCAM; N-CAM-1; Ncam; NCAM-1; Ncam1; Neural cell adhesion molecule 1
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Gene Symbols: Ncam1
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Molecular weight:
119,427 Da
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Basal Isoelectric point:
4.73
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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