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NSBP1
Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. Belongs to the HMGN family. Ubiquitously expressed. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding |
| Chromosomal Location of human Ortholog: Xq21.1 |
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Cellular Component:
chromatin; mitochondrion; nucleoplasm; nucleus
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Molecular Function:
chromatin binding; nucleosomal DNA binding
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Biological Process:
chromatin organization; negative regulation of apoptotic process; positive regulation of cell population proliferation; positive regulation of DNA-templated transcription; positive regulation of gene expression; regulation of DNA-templated transcription
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Reference #:
P82970
(UniProtKB)
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Alt. Names/Synonyms: high mobility group nucleosome binding domain 5; High mobility group nucleosome-binding domain-containing protein 5; high-mobility group nucleosome binding domain 5; HMGN5; NBP-45; NSBP1; nucleosomal binding protein 1; Nucleosome-binding protein 1
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Gene Symbols: HMGN5
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Molecular weight:
31,525 Da
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Basal Isoelectric point:
4.5
Predict pI for various phosphorylation states
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