|
EEF1AKMT4-ECE2
Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity. May play a role in amyloid-beta processing. In the C-terminal section; belongs to the peptidase M13 family. 1 alternatively spliced human isoform has been reported. Note: This description may include information from UniProtKB.
|
| Chromosomal Location of human Ortholog: 3q27.1 |
|
Cellular Component:
Golgi membrane; plasma membrane; transport vesicle membrane
|
|
Molecular Function:
metal ion binding; metalloendopeptidase activity; S-adenosylmethionine-dependent methyltransferase activity
|
|
Biological Process:
brain development; cardioblast differentiation; heart development; methylation; protein processing
|
|
Reference #:
P0DPD8
(UniProtKB)
|
|
Alt. Names/Synonyms: ECE-2; ECE2; EEF1AKMT4-ECE2; EEF1AKMT4-ECE2 readthrough; EEF1AKMT4-ECE2 readthrough transcript protein; EFCE2; Endothelin-converting enzyme 2; Endothelin-converting enzyme 2 region; Methyltransferase-like region
|
|
Gene Symbols: EEF1AKMT4-ECE2
|
|
Molecular weight:
99,773 Da
|
|
Basal Isoelectric point:
4.98
Predict pI for various phosphorylation states
|
