PGM1 This enzyme participates in both the breakdown and synthesis of glucose. Belongs to the phosphohexose mutase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - starch and sucrose; EC 5.4.2.2; Isomerase
Chromosomal Location of human Ortholog: 1p31.3
Cellular Component:  cytoplasm; cytosol; extracellular region; ficolin-1-rich granule lumen; tertiary granule lumen
Molecular Function:  magnesium ion binding; phosphoglucomutase activity; protein binding
Biological Process:  carbohydrate metabolic process; gluconeogenesis; glucose metabolic process; glycolytic process
Disease: Congenital Disorder Of Glycosylation, Type It
Reference #:  P36871 (UniProtKB)
Alt. Names/Synonyms: CDG1T; Glucose phosphomutase 1; GSD14; PGM 1; PGM1; phosphoglucomutase 1; Phosphoglucomutase-1
Gene Symbols: PGM1
Molecular weight: 61,449 Da
Basal Isoelectric point: 6.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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PGM1

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein