PGM1
This enzyme participates in both the breakdown and synthesis of glucose. Belongs to the phosphohexose mutase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - starch and sucrose; EC 5.4.2.2; Isomerase |
Chromosomal Location of human Ortholog: 1p31.3 |
Cellular Component:
cytoplasm; cytosol; extracellular region; ficolin-1-rich granule lumen; tertiary granule lumen
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Molecular Function:
magnesium ion binding; phosphoglucomutase activity; protein binding
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Biological Process:
carbohydrate metabolic process; gluconeogenesis; glucose metabolic process; glycolytic process
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Disease: Congenital Disorder Of Glycosylation, Type It
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Reference #:
P36871
(UniProtKB)
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Alt. Names/Synonyms: CDG1T; Glucose phosphomutase 1; GSD14; PGM 1; PGM1; phosphoglucomutase 1; Phosphoglucomutase-1
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Gene Symbols: PGM1
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Molecular weight:
61,449 Da
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Basal Isoelectric point:
6.3
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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