SNX12 May be involved in several stages of intracellular trafficking. Belongs to the sorting nexin family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of human Ortholog: Xq13.1
Cellular Component:  early endosome; early endosome membrane; retromer complex
Molecular Function:  enzyme binding; phosphatidylinositol binding; phosphatidylinositol-3-phosphate binding; protein binding
Biological Process:  endocytic recycling; late endosome to Golgi transport; negative regulation of early endosome to late endosome transport; negative regulation of gene expression; negative regulation of protein catabolic process; negative regulation of protein processing; negative regulation of protein transport; protein transport; regulation of endocytosis
Reference #:  Q9UMY4 (UniProtKB)
Alt. Names/Synonyms: MGC118982; MGC118983; SNX12; sorting nexin 12; Sorting nexin-12
Gene Symbols: SNX12
Molecular weight: 18,885 Da
Basal Isoelectric point: 8.58  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein