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TXNDC1
May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Ubiquitous. Highly expressed in kidney, liver, placenta and lung. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral |
| Chromosomal Location of human Ortholog: 14q22.1 |
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Cellular Component:
endomembrane system; endoplasmic reticulum membrane
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Molecular Function:
disulfide oxidoreductase activity; protein binding
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Biological Process:
response to endoplasmic reticulum stress
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Reference #:
Q9H3N1
(UniProtKB)
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Alt. Names/Synonyms: DKFZp564E1962; PDIA11; protein disulfide isomerase family A, member 11; thioredoxin domain containing 1; Thioredoxin domain-containing protein 1; thioredoxin related transmembrane protein 1; Thioredoxin-related transmembrane protein 1; TMX; TMX1; Transmembrane Trx-related protein; TXNDC; TXNDC1
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Gene Symbols: TMX1
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Molecular weight:
31,791 Da
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Basal Isoelectric point:
4.91
Predict pI for various phosphorylation states
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