RBM10 May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A). May bind to specific miRNA hairpins. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; RNA splicing; RNA-binding
Chromosomal Location of Human Ortholog: Xp11.3
Cellular Component:  nuclear speck; nucleus; protein-containing complex
Molecular Function:  identical protein binding; metal ion binding; miRNA binding; protein binding
Biological Process:  3'-UTR-mediated mRNA stabilization; mRNA processing; negative regulation of cell proliferation; negative regulation of mRNA splicing, via spliceosome; negative regulation of transcription by RNA polymerase II; positive regulation of smooth muscle cell apoptotic process; regulation of alternative mRNA splicing, via spliceosome; RNA splicing
Disease: Tarp Syndrome
Reference #:  P98175 (UniProtKB)
Alt. Names/Synonyms: DXS8237E; G patch domain-containing protein 9; GPATC9; GPATCH9; KIAA0122; MGC1132; MGC997; RBM10; RNA binding motif protein 10; RNA-binding motif protein 10; RNA-binding protein 10; RNA-binding protein S1-1; S1-1; ZRANB5
Gene Symbols: RBM10
Molecular weight: 103,533 Da
Basal Isoelectric point: 5.69  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein