FKBP15 May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase. Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement. Belongs to the FKBP-type PPIase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: 9q32
Cellular Component:  early endosome; membrane
Molecular Function:  actin binding; protein binding
Biological Process:  endocytosis; negative regulation of phosphatase activity
Reference #:  Q5T1M5 (UniProtKB)
Alt. Names/Synonyms: 133 kDa FK506-binding protein; 133 kDa FKBP; FK506 binding protein 15, 133kDa; FK506-binding protein 133kDa; FK506-binding protein 15; FKB15; FKBP prolyl isomerase 15; FKBP prolyl isomerase family member 15; FKBP-133; FKBP-15; FKBP133; FKBP15; KIAA0674; PPP1R76; protein phosphatase 1, regulatory subunit 76; WAFL; WASP and FKBP-like; WASP and FKBP-like protein; WASP- and FKBP-like protein
Gene Symbols: FKBP15
Molecular weight: 133,630 Da
Basal Isoelectric point: 5.11  Predict pI for various phosphorylation states
Select Structure to View Below

FKBP15

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene