DYNC1I2 iso3 intermediate chain 2 of dynein. The intermediate chains seem to help dynein bind to dynactin 150 kDa component. The dynein complex is involved in microtubule motor activity and consists of at least two heavy chains and a number of intermediate and light chains. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component:  centrosome; cytoplasm; cytosol; microtubule; vesicle
Molecular Function:  microtubule motor activity; protein binding
Biological Process:  antigen processing and presentation of exogenous peptide antigen via MHC class II; ciliary basal body-plasma membrane docking; ER to Golgi vesicle-mediated transport; G2/M transition of mitotic cell cycle; microtubule-based movement; regulation of G2/M transition of mitotic cell cycle; viral process
Reference #:  Q13409-3 (UniProtKB)
Alt. Names/Synonyms: Cytoplasmic dynein 1 intermediate chain 2; Cytoplasmic dynein intermediate chain 2; DC1I2; DH IC-2; DNCI2; DNCIC2; DYNC1I2; Dynein intermediate chain 2, cytosolic; dynein, cytoplasmic 1, intermediate chain 2; dynein, cytoplasmic, intermediate polypeptide 2; FLJ21089; FLJ90842; IC2; MGC104199; MGC111094; MGC9324
Gene Symbols: DYNC1I2
Molecular weight: 68,426 Da
Basal Isoelectric point: 5.16  Predict pI for various phosphorylation states
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DYNC1I2 iso3

Protein Structure Not Found.


Cross-references to other databases:  cBioPortal  |  Wikipedia  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein