TBC1D10B Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, AND RAB35. Does not act on RAB2A and RAB6A. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rab
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component:  cytosol; plasma membrane
Molecular Function:  GTPase activator activity; protein binding
Biological Process:  regulation of GTPase activity; retrograde transport, endosome to Golgi
Reference #:  Q4KMP7 (UniProtKB)
Alt. Names/Synonyms: DKFZp434P1750; FP2461; TB10B; TBC1 domain family member 10B; TBC1 domain family, member 10B; TBC1D10B
Gene Symbols: TBC1D10B
Molecular weight: 87,199 Da
Basal Isoelectric point: 9.27  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein