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ANXA9
Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes. Belongs to the annexin family. Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). Note: This description may include information from UniProtKB.
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| Protein type: Calcium-binding; Lipid-binding |
| Chromosomal Location of human Ortholog: 1q21.3 |
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Cellular Component:
cell surface; cytoplasm; cytosol; extracellular space; nucleus; plasma membrane; synapse; vesicle
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Molecular Function:
acetylcholine receptor activity; calcium channel activity; calcium ion binding; calcium-dependent phospholipid binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; phospholipase A2 inhibitor activity; phospholipid binding; protease binding; protein binding; virion binding
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Biological Process:
calcium ion transmembrane transport; cell-cell adhesion; negative regulation of catalytic activity; synaptic transmission, cholinergic
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Reference #:
O76027
(UniProtKB)
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Alt. Names/Synonyms: annexin 31; Annexin A9; Annexin XXXI; Annexin-31; Annexin-9; ANX31; anxa 9; ANXA9; Pemphaxin
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Gene Symbols: ANXA9
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Molecular weight:
38,364 Da
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Basal Isoelectric point:
5.53
Predict pI for various phosphorylation states
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