ANXA9 Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes. Belongs to the annexin family. Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Lipid-binding
Chromosomal Location of human Ortholog: 1q21.3
Cellular Component:  cell surface; cytoplasm; cytosol; extracellular space; nucleus; plasma membrane; synapse; vesicle
Molecular Function:  acetylcholine receptor activity; calcium channel activity; calcium ion binding; calcium-dependent phospholipid binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; phospholipase A2 inhibitor activity; phospholipid binding; protease binding; protein binding; virion binding
Biological Process:  calcium ion transmembrane transport; cell-cell adhesion; negative regulation of catalytic activity; synaptic transmission, cholinergic
Reference #:  O76027 (UniProtKB)
Alt. Names/Synonyms: annexin 31; Annexin A9; Annexin XXXI; Annexin-31; Annexin-9; ANX31; anxa 9; ANXA9; Pemphaxin
Gene Symbols: ANXA9
Molecular weight: 38,364 Da
Basal Isoelectric point: 5.53  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene