ZNF828 Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; RNA-binding
Chromosomal Location of Human Ortholog: 13q34
Cellular Component:  condensed chromosome; condensed chromosome kinetochore; cytoplasm; Flemming body; nucleoplasm; nucleus; spindle
Molecular Function:  metal ion binding; nucleic acid binding; protein binding
Biological Process:  attachment of mitotic spindle microtubules to kinetochore; protein localization to kinetochore; protein localization to microtubule; sister chromatid biorientation
Disease: Mental Retardation, Autosomal Dominant 40
Reference #:  Q96JM3 (UniProtKB)
Alt. Names/Synonyms: C13orf8; Chromosome alignment-maintaining phosphoprotein 1; FLJ90413; KIAA1802; Zinc finger protein 828; ZN828; ZNF828
Gene Symbols: CHAMP1
Molecular weight: 89,099 Da
Basal Isoelectric point: 8.7  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein