ZNF318 Isoform 2: Acts as a transcriptional corepressor for AR-mediated transactivation function. May act as a transcriptional regulator during spermatogenesis and, in particular, during meiotic division. Isoform 1: Acts as a transcriptional coactivator for AR-mediated transactivation function. May act as a transcriptional regulator during spermatogenesis and, in particular, during meiotic division. Expressed in endocrine tissue. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component:  cytosol; nucleoplasm
Molecular Function:  nucleic acid binding; protein homodimerization activity; zinc ion binding
Biological Process:  meiotic cell cycle; negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated
Reference #:  Q5VUA4 (UniProtKB)
Alt. Names/Synonyms: endocrine regulator; Endocrine regulatory protein; FLJ21852; HRIHFB2436; testicular zinc finger; TZF; ZFP318; Zinc finger protein 318; ZN318; ZNF318
Gene Symbols: ZNF318
Molecular weight: 251,112 Da
Basal Isoelectric point: 6.78  Predict pI for various phosphorylation states
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ZNF318

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  NURSA