|
SHCBP1
May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells. Note: This description may include information from UniProtKB.
|
| Protein type: Adaptor/scaffold |
| Chromosomal Location of human Ortholog: 16q11.2 |
|
Cellular Component:
cytoplasm; midbody; spindle
|
|
Molecular Function:
protein binding; SH2 domain binding
|
|
Biological Process:
fibroblast growth factor receptor signaling pathway; regulation of neural precursor cell proliferation
|
|
Reference #:
Q8NEM2
(UniProtKB)
|
|
Alt. Names/Synonyms: FLJ22009; MGC26900; PAL; Protein expressed in Activated Lymphocytes; SHC binding and spindle associated 1; SHC SH2 domain-binding protein 1; SHC SH2-domain binding protein 1; SHCBP; SHCBP1
|
|
Gene Symbols: SHCBP1
|
|
Molecular weight:
75,690 Da
|
|
Basal Isoelectric point:
4.66
Predict pI for various phosphorylation states
|
