CBCP1 Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription. Belongs to the cyclin family. Cyclin Y subfamily. Widely expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 10p11.21
Cellular Component:  cytoplasmic cyclin-dependent protein kinase holoenzyme complex; nucleus; plasma membrane
Molecular Function:  cyclin-dependent protein serine/threonine kinase regulator activity; protein binding; protein kinase binding
Biological Process:  cell division; G2/M transition of mitotic cell cycle; positive regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of canonical Wnt signaling pathway; Wnt signaling pathway
Reference #:  Q8ND76 (UniProtKB)
Alt. Names/Synonyms: C10orf9; CBCP1; CCNX; CCNY; CFP1; Cyc-Y; Cyclin box protein 1; Cyclin fold protein 1; cyclin Y; cyclin-box carrying protein 1; cyclin-X; Cyclin-Y; FLJ95513
Gene Symbols: CCNY
Molecular weight: 39,337 Da
Basal Isoelectric point: 6.76  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein