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alphaSNBP(A)
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs. Belongs to the LSM14 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: RNA-binding; Translation |
| Chromosomal Location of human Ortholog: 19q13.11 |
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Cellular Component:
cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; cytosol; mitotic spindle; P-body; ribonucleoprotein complex
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Molecular Function:
double-stranded DNA binding; double-stranded RNA binding; mRNA binding; protein binding; single-stranded RNA binding
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Biological Process:
defense response to virus; mitotic spindle assembly; negative regulation of translation; P-body assembly; positive regulation of type I interferon-mediated signaling pathway; RIG-I signaling pathway; stress granule assembly
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Reference #:
Q8ND56
(UniProtKB)
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Alt. Names/Synonyms: AlphaSNBP; alphaSNBP(A); C19orf13; DKFZp434D1335; FAM61A; family with sequence similarity 61, member A; hRAP55; hRAP55A; LS14A; LSM14 homolog A; LSM14A; LSM14A mRNA processing body assembly factor; LSM14A, SCD6 homolog A; LSM14A, SCD6 homolog A (S. cerevisiae); Protein FAM61A; Protein LSM14 homolog A; Protein SCD6 homolog; Putative alpha-synuclein-binding protein; RAP55; RAP55A; RNA-associated protein 55; RNA-associated protein 55A
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Gene Symbols: LSM14A
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Molecular weight:
50,530 Da
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Basal Isoelectric point:
9.55
Predict pI for various phosphorylation states
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