EPB41L1 iso4 May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 2 H1|2 77.39 cM
Cellular Component:  cytoplasm; cytoskeleton; plasma membrane; postsynaptic density; protein-containing complex; synaptic membrane
Molecular Function:  actin binding; cytoskeletal protein binding; protein binding; signaling receptor binding; structural molecule activity
Biological Process:  actomyosin structure organization; cortical actin cytoskeleton organization
Reference #:  E9PV14 (UniProtKB)
Alt. Names/Synonyms: 4.1; 4.1N; Band 4.1-like protein 1; Epb4.1; Epb4.1l1; Epb41l1; EPB41L1 iso4; erythrocyte membrane protein band 4.1 like 1; erythrocyte protein band 4.1 like 1; erythrocyte protein band 4.1-like 1; mKIAA0338; NBL1; neuronal protein 4.1; OTTMUSP00000016920; OTTMUSP00000016923; OTTMUSP00000017082
Gene Symbols: Epb4.1l1
Molecular weight: 117,172 Da
Basal Isoelectric point: 5.64  Predict pI for various phosphorylation states
Select Structure to View Below

EPB41L1 iso4

Protein Structure Not Found.

Cross-references to other databases:  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  Ensembl Protein