SAMD4B Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A. Belongs to the SMAUG family. Widely expressed in embryonic and adult tissues. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: 19q13.2
Cellular Component:  cytosol; nucleus; P-body
Molecular Function:  mRNA binding; protein binding; translation repressor activity
Biological Process:  nuclear-transcribed mRNA poly(A) tail shortening
Reference #:  Q5PRF9 (UniProtKB)
Alt. Names/Synonyms: FLJ10211; hSmaug2; MGC99832; Protein Smaug homolog 2; SAM domain-containing protein 4B; SAMD4B; SMAG2; Smaug 2; smaug homolog B; SMAUG2; SMGB; sterile alpha motif domain containing 4B; Sterile alpha motif domain-containing protein 4B
Gene Symbols: SAMD4B
Molecular weight: 75,483 Da
Basal Isoelectric point: 6.37  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene