DDX29 ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity. Belongs to the DEAD box helicase family. DEAH subfamily. Note: This description may include information from UniProtKB.
Protein type: EC; Helicase; Translation
Chromosomal Location of Human Ortholog: 5q11.2
Cellular Component:  eukaryotic 43S preinitiation complex
Molecular Function:  ATP binding; ribosomal small subunit binding; translation initiation factor activity
Biological Process:  positive regulation of translational initiation; translational initiation
Reference #:  Q7Z478 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent RNA helicase DHX29; DDX29; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29; DEAH (Asp-Glu-Ala-His) box polypeptide 29; DEAH box protein 29; DEAH-box helicase 29; DExH-box helicase 29; DHX29; FLJ21492; Nucleic acid helicase DDXx
Gene Symbols: DHX29
Molecular weight: 155,236 Da
Basal Isoelectric point: 8.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB