GATAD2A Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B. Ubiquitous, both in fetal and adult tissues. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 19p13.11
Cellular Component:  nuclear speck; nucleoplasm; nucleus; NuRD complex
Molecular Function:  DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; protein binding, bridging; sequence-specific DNA binding; zinc ion binding
Biological Process:  DNA methylation; negative regulation of transcription, DNA-templated
Reference #:  Q86YP4 (UniProtKB)
Alt. Names/Synonyms: FLJ20085; FLJ21017; GATA zinc finger domain containing 2A; GATA zinc finger domain-containing protein 2A; GATAD2A; Hp66alpha; p66 alpha; P66A; p66alpha; Transcriptional repressor p66-alpha
Gene Symbols: GATAD2A
Molecular weight: 68,063 Da
Basal Isoelectric point: 9.95  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

GATAD2A

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene