GON4L Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 1q22
Cellular Component:  nuclear body; nucleoplasm; nucleus
Molecular Function:  DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription corepressor activity
Biological Process:  B cell differentiation; negative regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II
Reference #:  Q3T8J9 (UniProtKB)
Alt. Names/Synonyms: 2610100B20Rik; DKFZp761I241; FLJ12923; FLJ20203; FLJ23040; GON-4; GON-4 homolog; gon-4-like (C. elegans); GON-4-like protein; GON4; GON4L; KIAA1606; MGC138817; MGC138818; RP11-243J18.4; YY1AP-related protein1
Gene Symbols: GON4L
Molecular weight: 248,620 Da
Basal Isoelectric point: 4.94  Predict pI for various phosphorylation states
Select Structure to View Below

GON4L

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein