KANSL1 As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. Expressed in the brain. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 17q21.31
Cellular Component:  condensed chromosome kinetochore; histone acetyltransferase complex; MLL1 complex; nucleoplasm; nucleus
Molecular Function:  protein binding
Biological Process:  histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation
Disease: Koolen-de Vries Syndrome
Reference #:  Q7Z3B3 (UniProtKB)
Alt. Names/Synonyms: CENP-36; centromere protein 36; DKFZp686P06109; DKFZp727C091; hMSL1v1; hypothetical protein LOC284058; K1267; KANL1; KANSL1; KAT8 regulatory NSL complex subunit 1; KDVS; KIAA1267; LOC284058; male-specific lethal 1 homolog; MGC102843; MLL1/MLL complex subunit KANSL1; MLL1/MLL complex subunit KIAA1267; MSL1 homolog 1; MSL1V1; Non-specific lethal 1 homolog; NSL complex protein NSL1; NSL1
Gene Symbols: KANSL1
Molecular weight: 121,025 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Select Structure to View Below

KANSL1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene