TAAR8 Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. Belongs to the G-protein coupled receptor 1 family. Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 6q23.2
Cellular Component:  integral component of membrane; plasma membrane
Molecular Function:  G protein-coupled receptor activity
Biological Process:  G protein-coupled receptor signaling pathway
Reference #:  Q969N4 (UniProtKB)
Alt. Names/Synonyms: G protein-coupled receptor 102; G-protein coupled receptor 102; GPR102; TA5; TAAR8; TaR-5; TaR-8; TAR5; trace amine associated receptor 8; Trace amine receptor 5; Trace amine receptor 8; Trace amine-associated receptor 8; TRAR5
Gene Symbols: TAAR8
Molecular weight: 38,029 Da
Basal Isoelectric point: 6.42  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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