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DDX46
Plays an essential role in splicing, either prior to, or during splicing A complex formation. Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.6.4.13; Helicase; Spliceosome |
| Chromosomal Location of human Ortholog: 5q31.1 |
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Cellular Component:
Cajal body; fibrillar center; membrane; nuclear speck; nucleoplasm; nucleus; spliceosomal complex; U2 snRNP
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Molecular Function:
ATP binding; ATP hydrolysis activity; protein binding; RNA helicase activity
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Biological Process:
mRNA splicing, via spliceosome; U2-type prespliceosome assembly
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Reference #:
Q7L014
(UniProtKB)
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Alt. Names/Synonyms: DDX46; DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; DEAD box protein 46; DEAD-box helicase 46; FLJ25329; KIAA0801; MGC9936; Probable ATP-dependent RNA helicase DDX46; Prp5; PRP5 homolog; Prp5-like DEAD-box protein; PRPF5; RNA helicase
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Gene Symbols: DDX46
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Molecular weight:
117,362 Da
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Basal Isoelectric point:
9.33
Predict pI for various phosphorylation states
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