DENND4B Guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Note: This description may include information from UniProtKB.
Protein type: GEF; GEF, Rab
Chromosomal Location of human Ortholog: 1q21.3
Cellular Component:  cytosol; Golgi apparatus; nucleus
Molecular Function:  Rab guanyl-nucleotide exchange factor activity
Biological Process:  regulation of Rab protein signal transduction
Reference #:  O75064 (UniProtKB)
Alt. Names/Synonyms: DEN4B; DENN domain containing 4B; DENN domain-containing protein 4B; DENN/MADD domain containing 4B; DENND4B; DKFZp762N174; FLJ26202; KIAA0476
Gene Symbols: DENND4B
Molecular weight: 163,847 Da
Basal Isoelectric point: 6.85  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene