SEPT3 Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. Brain-specific. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Cytoskeletal; Hydrolase
Chromosomal Location of human Ortholog: 22q13.2
Cellular Component:  cell division site; microtubule cytoskeleton; neuron projection; presynapse; presynaptic cytoskeleton; septin complex; septin ring
Molecular Function:  GTP binding; GTPase activity; identical protein binding; molecular adaptor activity; protein binding
Biological Process:  cytoskeleton-dependent cytokinesis; protein localization
Reference #:  Q9UH03 (UniProtKB)
Alt. Names/Synonyms: bK250D10.3; MGC133218; neuronal-specific septin 3; Neuronal-specific septin-3; SEP3; SEPT3; septin 3; SEPTIN3
Gene Symbols: SEPTIN3
Molecular weight: 40,704 Da
Basal Isoelectric point: 6.74  Predict pI for various phosphorylation states
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SEPT3

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein