hnRNP F Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state. Expressed ubiquitously. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 10q11.21
Cellular Component:  catalytic step 2 spliceosome; cytosol; nucleoplasm; nucleus; plasma membrane
Molecular Function:  protein binding; single-stranded RNA binding; TBP-class protein binding
Biological Process:  fibroblast growth factor receptor signaling pathway; interleukin-12-mediated signaling pathway; mRNA splicing, via spliceosome; regulation of RNA splicing; RNA metabolic process; RNA processing
Reference #:  P52597 (UniProtKB)
Alt. Names/Synonyms: Heterogeneous nuclear ribonucleoprotein F; Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; hnRNP F; HnRNP F protein; HNRNPF; HNRPF; mcs94-1; MGC110997; Nucleolin-like protein mcs94-1; OK/SW-cl.23
Gene Symbols: HNRNPF
Molecular weight: 45,672 Da
Basal Isoelectric point: 5.38  Predict pI for various phosphorylation states
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hnRNP F

Protein Structure Not Found.


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