FANCG DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene. Highly expressed in testis and thymus. Found in lymphoblasts. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage
Chromosomal Location of mouse Ortholog: 4|4 A5
Cellular Component:  chromatin; cytosol; Fanconi anaemia nuclear complex; mitochondrion; nucleolus; nucleus; plasma membrane
Biological Process:  DNA damage response; DNA repair; interstrand cross-link repair; mitochondrion organization; ovarian follicle development; protein monoubiquitination; response to radiation; spermatid development
Reference #:  Q9EQR6 (UniProtKB)
Alt. Names/Synonyms: AU041407; Fancg; Fanconi anemia group G protein homolog; Fanconi anemia, complementation group G; OTTMUSP00000007084; Protein FACG; Xrcc; Xrcc9
Gene Symbols: Fancg
Molecular weight: 68,506 Da
Basal Isoelectric point: 5.25  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein