DHX38 iso2
Probable ATP-binding RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
Protein type: EC 3.6.4.13; Helicase; RNA processing; RNA splicing; RNA-binding; Spliceosome |
Chromosomal Location of human Ortholog: 16q22.2 |
Cellular Component:
catalytic step 2 spliceosome; intracellular anatomical structure; nucleoplasm; nucleus; spliceosomal complex
|
Molecular Function:
3'-5' RNA helicase activity; ATP binding; ATP hydrolysis activity; protein binding; RNA binding; RNA helicase activity
|
Biological Process:
mRNA splicing, via spliceosome
|
Reference #:
Q92620-2
(UniProtKB)
|
Alt. Names/Synonyms: ATP-dependent RNA helicase DHX38; DDX38; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 38; DEAH (Asp-Glu-Ala-His) box polypeptide 38; DEAH box protein 38; DEAH-box helicase 38; DHX38; DHX38 iso2; KIAA0224; Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; PRP16; PRP16 homolog of S.cerevisiae; PRPF16; RP84
|
Gene Symbols: DHX38
|
Molecular weight:
60,743 Da
|
Basal Isoelectric point:
6.81
Predict pI for various phosphorylation states
|