Ferritin-H
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Belongs to the ferritin family. Expressed in the liver. Note: This description may include information from UniProtKB.
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Protein type: Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.16.3.1; Oxidoreductase |
Chromosomal Location of mouse Ortholog: 19 A|19 6.23 cM |
Cellular Component:
autolysosome; cytoplasm; endocytic vesicle lumen; extracellular region
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Molecular Function:
ferric iron binding; ferrous iron binding; ferroxidase activity; identical protein binding; iron ion binding; iron ion sequestering activity; metal ion binding; oxidoreductase activity
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Biological Process:
intracellular iron ion homeostasis; intracellular sequestering of iron ion; iron ion transport; negative regulation of fibroblast proliferation
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Reference #:
P09528
(UniProtKB)
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Alt. Names/Synonyms: AL022624; AL033366; Ferritin H subunit; Ferritin heavy chain; ferritin heavy chain 1; Ferritin heavy chain, N-terminally processed; ferritin heavy polypeptide 1; Ferritin-H; FHC; FRIH; Fth; Fth1; H-fer; H-ferritin; HFt; MFH
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Gene Symbols: Fth1
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Molecular weight:
21,067 Da
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Basal Isoelectric point:
5.53
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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